• br Ubiquitin ligases Ubiquitin ligases are categorized into

  2020-04-17

  

  Ubiquitin ligases Ubiquitin ligases are categorized into different Spadin mg based on their specific structural configuration and the composition of subunits—HECT (homologous to E6-AP1 (E6-associated protein 1) carboxy-terminus)-type, RING (really interesting new gene)-finger-type, U-box-type, or

• br Author Contributions Statement br Conflicts of

  2020-04-17

  

  Author Contributions Statement Conflicts of interest Acknowledgments We thank T. Ishii, H. Inaba, and S. Nakamura (Department of Cell Biology, TMDU) for kindly gifting BACCS and technical assistance; S. Kaneko, Y. Ishida, and R. Usumi (Department of Orthodontic Science, TMDU) for experiment

• We found that the postnatal absence of

  2020-04-17

  

  We found that the postnatal absence of norepinephrine yields differing effects depending on noradrenergic receptor type and Sodium Picosulfate australia region. The density of α1-AR, indicated by [3H]prazosin binding was similar between Dbh+/− and Dbh−/− mice except for a significant increase in hi

• Contrary to the profuse dopaminergic innervation of the

  2020-04-17

  

  Contrary to the profuse dopaminergic innervation of the thalamus found in human and non-human primates (Brown et al., 1979, Sanchez-Gonzalez et al., 2005), in rodents, the RTn is one the few thalamic nuclei that receives dopaminergic input (Anaya-Martinez et al., 2006, Garcia-Cabezas et al., 2007, G

• Considering the divergence of multiple DGAT isoforms we exam

  2020-04-17

  

  Considering the divergence of multiple DGAT isoforms, we examined whether MiDGAT1 and MiDGAT2s utilized different fatty acids as the substrate to synthesize TAGs. GC-MS analysis indicated that C16:0 and C18:0 were the major components of TAGs in yeast cells, and all three MiDGATs displayed the same

• br Conclusions In conclusion we identified and overexpressed

  2020-04-17

  

  Conclusions In conclusion, we identified and overexpressed DGAT2 in fast growing, oleaginous N. oceanica for the first time. The engineered N. oceanica overexpressing DGAT2 resulted in enhanced neutral lipid accumulation and altered fatty Ranolazine composition. Altogether, our findings demonstr

• INO-1001 Many filarial species harbor an endosymbiotic bacte

  2020-04-17

  

  Many filarial species harbor an endosymbiotic bacterium of the genus Wolbachia. A recent investigation of Wolbachia distribution in 35 filarial species including 28 species and 7 genera and/or subgenera have shown that 37% of them harbor Wolbachia (Ferri et al., 2011). In filarial nematodes, Wolbach

• br Prostaglandin D PGD is derived from the metabolism of

  2020-04-17

  

  Prostaglandin D (PGD) is derived from the metabolism of arachidonic Phleomycin by cyclooxygenases and downstream PGD synthases. In the immune system, PGD is mainly produced by mast cells but also although at lower levels, by macrophages and Th2 lymphocytes. PGD binds to three different receptors,

• Pattern separation is a process that

  2020-04-17

  

  Pattern separation is a process that takes place in the hippocampus and more specifically in the dentate gyrus (DG) and Cornu Ammonis region 3 (CA3) (Morris, Churchwell, Kesner, & Gilbert, 2012). The main source of input in the hippocampus is derived from the enthorinal cortex (EC) that mainly proje

• The observed increase in Bdnf mRNA occurred h after

  2020-04-17

  

  The observed increase in Bdnf1 mRNA occurred 1 h after treatment indicates participation of BDNF in early plasticity and subsequently mnemonic processes. Most of the evidence regarding the importance of BDNF for memory formation derived from electrophysiological studies that utilized the molecular c

• No orthologs could be found

  2020-04-17

  

  No orthologs could be found in our B. oleracea BAC library for AtCk1/2, which could mean that it is unique to Arabidopsis, or that we failed to detect it in our library. However, the second possibility is unlikely considering that Southern blotting analysis with four restriction enzymes disclosed fr

• Other membrane currents are affected

  2020-04-17

  

  Other membrane currents are affected as well. Some studies have provided evidence that sulfonylureas, in addition to blocking KATP channels, also inhibit chloride and calcium channels. GLYB has been shown to almost inhibit the current generated by Na+–K+ pumps in a concentration-dependent manner (wi

• There is an opposite opinion indicating that

  2020-04-17

  

  There is an opposite opinion indicating that EphB plays a role as cancer suppressor. Batlle et al. showed that loss of EphB expression represented a critical step in CRC progression, and CRCs that lacked EphB2 expression have been correlated with more advanced tumour stage, poor differentiation, and

• Acidosis has lethal consequences but alkalosis due to

  2020-04-17

  

  Acidosis has lethal consequences, but alkalosis (due to chloride depletion, potassium depletion, and excess mineralocorticoid) is not tolerated as well (Luke and Galla, 2012). In this regard, efforts to restore pH to normal physiological level, in the most benign way should be the goal of researcher

• CSN was initially identified based on the constitutitvely ph

  2020-04-16

  

  CSN was initially identified based on the constitutitvely photormophogenic (cop) mutants from Arabidopsis thaliana [48]. csn mutants are Cullin deneddylation-deficient, consequently accumulate neddylated Cullins, and arrest growth shortly after germination [49, 50, 51]. Weak csn mutants have defects

15765 records 852/1051 page Previous Next First page 上5页 851852853854855 下5页 Last page