• Silk which is a mixture of mainly SF

  2024-11-06

  

  Silk, which is a mixture of mainly SF and sericin, has an extensive history in clinical application as a suture material. Unwanted immune reactions to silk sutures observed early on in their application were assigned to the presence of sericin. However, in vitro and in vivo evaluations of pure SF fi

• PAN induced nephrosis was accompanied

  2024-11-06

  

  PAN-induced nephrosis was accompanied by loss of body weight, decrease of food intake, increase in urine volume and increases in triglycerides and cholesterol levels, which have been reported previously (Natori et al., 1996). Except for urine volume, each one of these measures was improved by A-3069

• A high throughput small molecule ACK biochemical

  2024-11-06

  

  A high-throughput small molecule ACK1 biochemical inhibition screen was performed in-house and led to the identification of 1μM inhibitor furanopyrimidine (). Further binding studies found NCT-502 to be both ATP-competitive and reversible. Early structure-activity relationship (SAR) work was perf

• br Patients and methods The severity of disease documented a

  2024-11-06

  

  Patients and methods The severity of disease documented at each outpatient visit was graded according to the modified Osserman classification: grade I, focal disease (e.g. restricted to ocular muscles); grade II, generalised disease that is mild (IIa) or moderate (IIb); grade III, severe general

• The present work has implications for our thinking about

  2024-11-06

  

  The present work has implications for our thinking about the effects of antidepressant (e.g. SSRIs) use on maternal care in depressed mothers which consist of approximately 10–20% of all mothers (Gjerdingen and Yawn, 2007, Susser et al., 2016), and more than 40% of depressed mothers are prescribed w

• br Expression of autotaxin in cancer Autotaxin ATX is a

  2024-11-06

  

  Expression of autotaxin in cancer Autotaxin (ATX) is a member of the family of NPPs (Nucleotides pyrophosphatases phosphodiesterases (NPP) family with a unique lysophospholipase D (lysoPLD) activity, allowing the synthesis of LPA from lysophospholipid precursors such as the lysophosphatidylcholin

• We also show that in both ATM proficient and

  2024-11-06

  

  We also show that in both ATM proficient and deficient/mutant SBHA the activation of ATR signaling is DSB complexity-dependent (Figs. 1, 4A, C and E, 6A and B). Wang et al. have also reported that the effects of ATR and CHK1 on radiosensitivity are independent of the NHEJ repair pathway [41], [42].

• br Concluding remarks It is clear that a disordered l

  2024-11-06

  

  Concluding remarks It is clear that a disordered l-arginine homeostasis by changes in arginase, NOS and ADMA activity and expression, is not only vital in the chronic airway diseases, Tenofovir and COPD, but also seems to play an important role in many co-morbidities. Unknown, however, is whethe

• The initial demonstration of the potential of MALDI

  2024-11-06

  

  The initial demonstration of the potential of MALDI-TOF MS for testing antifungal susceptibility of pathogenic fungi came from a proof-of-concept study by Marinach et al. [31] who monitored the changes of the proteome of C. albicans HOAt exposed to different concentrations of fluconazole. Using a ri

• A previous review article suggested different washout interv

  2024-11-06

  

  A previous review article suggested different washout intervals based on specific clinical contexts [4]. While no consensus was reached for the optimal interval between last dose of BV and surgery for CRLM, the authors of the review suggested waiting 6 to 8 weeks after BV before surgery, particular

• Consistent with the in vitro results memantine ameliorated A

  2024-11-05

  

  Consistent with the in vitro results, memantine ameliorated Aβ-induced cytotoxicity in rat primary cortical cultures. Studies reported that memantine protected neurons against the damage caused by aggregated Aβ40 or Aβ42 oligomers in vivo[26], [27]. These results suggest that, in addition to its neu

• br Materials and met http www apexbt

  2024-11-05

  

  Materials and methods Results The values for body weight are shown in Fig. 1. Body weight was measured every day. The body weight of the young mice in the control (i.e. no-stress) group was not significantly different from that of the young mice in the stress group. However, the middle-aged mi

• Scutellaria moniliorrhiza Komarov Labiatae is

  2024-11-05

  

  Scutellaria moniliorrhiza Komarov (Labiatae) is a perennial herb and mainly distributed in Jilin province, China. In traditional Chinese medicine, the whole plants have been used to clear away heat-evil, expel superficial evils, eliminate stasis and reduce edema (He et al., 2012). In previous phytoc

• br Methods br Results br Discussion Chronic

  2024-11-05

  

  Methods Results Discussion Chronic stress renders individuals vulnerable to diseases, and this effect might be, at least partially, mediated by stress hormone-induced immunosuppression. Therefore, investigating the effects of catecholamines on immune MK-4827 hydrochloride is of high releva

• br Conclusions Triptans are HT B D F

  2024-11-05

  

  Conclusions Triptans are 5-HT1B/1D/(1F) receptors agonists and are considered as the gold standard for acute migraine treatment that have been proven effective. Unfortunately, they are contraindicated in patients with cardiovascular diseases due to their vasoconstrictor (side) effects (MaassenVan

15762 records 68/1051 page Previous Next First page 上5页 6667686970 下5页 Last page